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HIV-associated nephropathy

MedGen UID:
37145
•Concept ID:
C0078911
•
Disease or Syndrome
Synonyms: AIDS Associated Nephropathies; AIDS Associated Nephropathy; AIDS Nephropathies; AIDS Nephropathy; AIDS-Associated Nephropathies; AIDS-Associated Nephropathy; HIV Associated Nephropathies; HIV Associated Nephropathy; HIV Related Nephropathies; HIV Related Nephropathy; HIV-Associated Nephropathies; HIV-Associated Nephropathy; HIV-Related Nephropathies; HIV-Related Nephropathy; Human Immunodeficiency Virus Associated Nephropathy; Human Immunodeficiency Virus-Associated Nephropathy; Nephropathies, AIDS; Nephropathies, AIDS Associated; Nephropathies, AIDS-Associated; Nephropathies, HIV Associated; Nephropathies, HIV Related; Nephropathies, HIV-Associated; Nephropathies, HIV-Related; Nephropathy, AIDS; Nephropathy, AIDS Associated; Nephropathy, AIDS-Associated; Nephropathy, HIV Associated; Nephropathy, HIV Related; Nephropathy, HIV-Associated; Nephropathy, HIV-Related
SNOMED CT: Acquired immune deficiency syndrome-related nephropathy (236406007); AIDS - Acquired immune deficiency synd-related nephropathy (236406007)
 
Monarch Initiative: MONDO:0005798

Definition

Renal disease in human immunodeficiency virus (HIV)-infected patients. It is characterized by nephrotic syndrome, azotemia, normal to large kidneys on ultrasound images, and focal segmental glomerulosclerosis on renal biopsy findings. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHIV-associated nephropathy

Professional guidelines

PubMed

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Pharmacotherapy and treatment options for HIV-associated nephropathy.
Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG
Expert Opin Pharmacother 2018 Jan;19(1):39-48. Epub 2017 Dec 26 doi: 10.1080/14656566.2017.1416099. PMID: 29224373Free PMC Article
The podocyte as a direct target for treatment of glomerular disease?
Mallipattu SK, He JC
Am J Physiol Renal Physiol 2016 Jul 1;311(1):F46-51. Epub 2016 Apr 20 doi: 10.1152/ajprenal.00184.2016. PMID: 27097894Free PMC Article

Recent clinical studies

Etiology

Digital spatial profiling of collapsing glomerulopathy.
Smith KD, Prince DK, Henriksen KJ, Nicosia RF, Alpers CE, Akilesh S
Kidney Int 2022 May;101(5):1017-1026. Epub 2022 Feb 26 doi: 10.1016/j.kint.2022.01.033. PMID: 35227689Free PMC Article
APOL1 Nephropathy: From Genetics to Clinical Applications.
Friedman DJ, Pollak MR
Clin J Am Soc Nephrol 2021 Feb 8;16(2):294-303. Epub 2020 Jul 2 doi: 10.2215/CJN.15161219. PMID: 32616495Free PMC Article
A focus on the association of Apol1 with kidney disease in children.
Ekulu PM, Nkoy AB, Adebayo OC, Kazadi OK, Aloni MN, Arcolino FO, Ngiyulu RM, Gini JE, Lepira FB, Van den Heuvel LP, Levtchenko EN
Pediatr Nephrol 2021 Apr;36(4):777-788. Epub 2020 Apr 6 doi: 10.1007/s00467-020-04553-z. PMID: 32253519
APOL1 risk variants and kidney disease: what we know so far.
Siemens TA, Riella MC, Moraes TP, Riella CV
J Bras Nefrol 2018 Oct-Dec;40(4):388-402. Epub 2018 Jul 26 doi: 10.1590/2175-8239-JBN-2017-0033. PMID: 30052698Free PMC Article
Most ApoL1 Is Secreted by the Liver.
Shukha K, Mueller JL, Chung RT, Curry MP, Friedman DJ, Pollak MR, Berg AH
J Am Soc Nephrol 2017 Apr;28(4):1079-1083. Epub 2016 Dec 8 doi: 10.1681/ASN.2016040441. PMID: 27932478Free PMC Article

Diagnosis

HIV Associated Nephropathy.
Alebiosu CO
West Afr J Med 2021 Apr 23;38(4):300-301. PMID: 33900703
Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
The podocyte as a direct target for treatment of glomerular disease?
Mallipattu SK, He JC
Am J Physiol Renal Physiol 2016 Jul 1;311(1):F46-51. Epub 2016 Apr 20 doi: 10.1152/ajprenal.00184.2016. PMID: 27097894Free PMC Article
Renal issues in HIV infection.
Kalayjian RC
Curr HIV/AIDS Rep 2011 Sep;8(3):164-71. doi: 10.1007/s11904-011-0080-x. PMID: 21643783
Ultrasonographic evaluation of renal infections.
Vourganti S, Agarwal PK, Bodner DR, Dogra VS
Radiol Clin North Am 2006 Nov;44(6):763-75. doi: 10.1016/j.rcl.2006.10.001. PMID: 17147985

Therapy

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
The podocyte as a direct target for treatment of glomerular disease?
Mallipattu SK, He JC
Am J Physiol Renal Physiol 2016 Jul 1;311(1):F46-51. Epub 2016 Apr 20 doi: 10.1152/ajprenal.00184.2016. PMID: 27097894Free PMC Article
Renal disease in AIDS: it is not always HIVAN.
Bani-Hani S, Patel V, Larsen CP, Walker PD, Cooke CR, Showkat A
Clin Exp Nephrol 2010 Jun;14(3):263-7. Epub 2010 Jan 6 doi: 10.1007/s10157-009-0253-8. PMID: 20049622
HIV-associated nephropathy.
Khan S, Haragsim L, Laszik ZG
Adv Chronic Kidney Dis 2006 Jul;13(3):307-13. doi: 10.1053/j.ackd.2006.04.013. PMID: 16815235
HIV-associated nephropathy.
Ross MJ, Klotman PE
AIDS 2004 May 21;18(8):1089-99. doi: 10.1097/00002030-200405210-00002. PMID: 15166524

Prognosis

Disseminated Monkeypox Infection in a Kidney Transplant Recipient: A Case Report.
Attieh RM, Brumble L, Elwasila SM, Wadei HM
Transplant Proc 2023 Apr;55(3):667-671. Epub 2023 Mar 21 doi: 10.1016/j.transproceed.2023.02.031. PMID: 36941151Free PMC Article
Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Renal issues in HIV infection.
Kalayjian RC
Curr HIV/AIDS Rep 2011 Sep;8(3):164-71. doi: 10.1007/s11904-011-0080-x. PMID: 21643783
HIV-associated nephropathy.
Khan S, Haragsim L, Laszik ZG
Adv Chronic Kidney Dis 2006 Jul;13(3):307-13. doi: 10.1053/j.ackd.2006.04.013. PMID: 16815235
Patients with HIV infection and end-stage renal disease.
Schoenfeld P, Rodriguez R, Mendelson M
Adv Ren Replace Ther 1996 Oct;3(4):287-92. doi: 10.1016/s1073-4449(96)80006-9. PMID: 8914690

Clinical prediction guides

Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Swanepoel CR, Atta MG, D'Agati VD, Estrella MM, Fogo AB, Naicker S, Post FA, Wearne N, Winkler CA, Cheung M, Wheeler DC, Winkelmayer WC, Wyatt CM; Conference Participants
Kidney Int 2018 Mar;93(3):545-559. Epub 2018 Feb 3 doi: 10.1016/j.kint.2017.11.007. PMID: 29398134Free PMC Article
Predictors of HIV-associated nephropathy.
Waheed S, Atta MG
Expert Rev Anti Infect Ther 2014 May;12(5):555-63. Epub 2014 Mar 21 doi: 10.1586/14787210.2014.901170. PMID: 24655211
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman OA, Uthman MM
Cochrane Database Syst Rev 2013 Jan 31;2013(1):CD007183. doi: 10.1002/14651858.CD007183.pub3. PMID: 23440812Free PMC Article
Renal issues in HIV infection.
Kalayjian RC
Curr HIV/AIDS Rep 2011 Sep;8(3):164-71. doi: 10.1007/s11904-011-0080-x. PMID: 21643783
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman AO, Uthman MM
Cochrane Database Syst Rev 2009 Oct 7;(4):CD007183. doi: 10.1002/14651858.CD007183.pub2. PMID: 19821397

Recent systematic reviews

MicroRNAs Associated with Chronic Kidney Disease in the General Population and High-Risk Subgroups-A Systematic Review.
Motshwari DD, Matshazi DM, Erasmus RT, Kengne AP, Matsha TE, George C
Int J Mol Sci 2023 Jan 16;24(2) doi: 10.3390/ijms24021792. PMID: 36675311Free PMC Article
Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.
Waziri B, Raji YE, Ekrikpo UE, Naicker S
J Nephrol 2023 May;36(4):1119-1134. Epub 2022 Dec 13 doi: 10.1007/s40620-022-01512-9. PMID: 36510118
Impact of Antiretroviral Therapy on Kidney Disease in HIV Infected Individuals - A Qualitative Systematic Review.
Adnani H, Agrawal N, Khatri A, Vialet J, Zhang M, Cervia J
J Int Assoc Provid AIDS Care 2022 Jan-Dec;21:23259582221089194. doi: 10.1177/23259582221089194. PMID: 35369795Free PMC Article
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman OA, Uthman MM
Cochrane Database Syst Rev 2013 Jan 31;2013(1):CD007183. doi: 10.1002/14651858.CD007183.pub3. PMID: 23440812Free PMC Article
Interventions for HIV-associated nephropathy.
Yahaya I, Uthman AO, Uthman MM
Cochrane Database Syst Rev 2009 Oct 7;(4):CD007183. doi: 10.1002/14651858.CD007183.pub2. PMID: 19821397

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